Optimal Bang-Bang Controls for a Two-Compartment Model in Cancer Chemotherapy
نویسندگان
چکیده
منابع مشابه
Optimal Bang-Bang Controls for a Two-Compartment Model in Cancer Chemotherapy
A class of mathematical models for cancer chemotherapy which have been described in the literature take the form of an optimal control problem over a finite horizon with control constraints and dynamics given by a bilinear system. In this paper, we analyze a twodimensional model in which the cell cycle is broken into two compartments. The cytostatic agent used as control to kill the cancer cell...
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ژورنال
عنوان ژورنال: Journal of Optimization Theory and Applications
سال: 2002
ISSN: 0022-3239,1573-2878
DOI: 10.1023/a:1016027113579